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Alexeeff, Stacey E.; Yau, Vincent; Qian, Yinge; Davignon, Meghan; Lynch, Frances; Crawford, Phillip; Davis, Robert; Croen, Lisa A. – Journal of Autism and Developmental Disorders, 2017
This study examines medical conditions diagnosed prior to the diagnosis of autism spectrum disorder (ASD). Using a matched case control design with 3911 ASD cases and 38,609 controls, we found that 38 out of 79 medical conditions were associated with increased ASD risk. Developmental delay, mental health, and neurology conditions had the strongest…
Descriptors: Autism, Pervasive Developmental Disorders, Clinical Diagnosis, Comorbidity
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Croen, Lisa A.; Shankute, Naomi; Davignon, Meghan; Massolo, Maria L.; Yoshida, Cathleen – Journal of Autism and Developmental Disorders, 2017
This study investigates demographic and clinical factors associated with initiation, continuation, and adherence to behavioral health treatment (BHT) among children with autism spectrum disorder. Among 293 insured children referred for applied behavior analysis (ABA) based BHT, 23% never initiated treatment. Among those initiating treatment, 31%…
Descriptors: Autism, Pervasive Developmental Disorders, Behavior Modification, Child Behavior
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Singer, Alison B.; Windham, Gayle C.; Croen, Lisa A.; Daniels, Julie L.; Lee, Brian K.; Qian, Yinge; Schendel, Diana E.; Fallin, M. Daniele; Burstyn, Igor – Journal of Autism and Developmental Disorders, 2016
Maternal immune activity has been linked to children with autism spectrum disorder (ASD). We examined maternal occupational exposure to asthma-causing agents during pregnancy in relation to ASD risk. Our sample included 463 ASD cases and 710 general population controls from the Study to Explore Early Development whose mothers reported at least one…
Descriptors: Autism, Pervasive Developmental Disorders, Mothers, Prenatal Influences
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Windham, Gayle C.; Lyall, Kristen; Anderson, Meredith; Kharrazi, Martin – Journal of Autism and Developmental Disorders, 2016
We examined prenatal screening markers and offspring autism spectrum disorder (ASD) using California statewide data on singleton births in 1996 and 2002. Second trimester levels of unconjugated estriol (uE3), human chorionic gonadotropin (hCG), and maternal serum alpha-fetoprotein (MSAFP) were compared between mothers of children with ASD…
Descriptors: Autism, Pervasive Developmental Disorders, Mothers, Regression (Statistics)
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Berryessa, Colleen M. – Journal of Autism and Developmental Disorders, 2016
This brief report presents preliminary data on the attitudes of judges on the sentencing of offenders with High Functioning Autism (HFA). Semi-structured telephone interviews were conducted with twenty-one California Superior Court Judges. Interviews were qualitatively coded and constant comparative analysis was utilized. Findings revealed that…
Descriptors: Autism, Pervasive Developmental Disorders, Severity (of Disability), Semi Structured Interviews
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Zerbo, Ousseny; Massolo, Maria L.; Qian, Yinge; Croen, Lisa A. – Journal of Autism and Developmental Disorders, 2015
We conducted an online survey of adult health care providers at Kaiser Permanente Northern California and semi-structured interviews with a subset of physicians. The survey assessed providers' ability to recognize autism spectrum disorder (ASD), asked them to rate their autism knowledge, comfort level in treating affected patients, and evaluated…
Descriptors: Autism, Pervasive Developmental Disorders, Physicians, Knowledge Level
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Zerbo, Ousseny; Qian, Yinge; Yoshida, Cathleen; Grether, Judith K.; Van de Water, Judy; Croen, Lisa A. – Journal of Autism and Developmental Disorders, 2015
We conducted a nested case-control study including 407 cases and 2,075 frequency matched controls to investigate the association between maternal infections during pregnancy and risk of autism spectrum disorders (ASD). Cases, controls, and maternal infections were ascertained from Kaiser Permanente Northern California clinical databases. No…
Descriptors: Autism, Pervasive Developmental Disorders, Mothers, Pregnancy
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Schieve, Laura A.; Fountain, Christine; Boulet, Sheree L.; Yeargin-Allsopp, Marshalyn; Kissin, Dmitry M.; Jamieson, Denise J.; Rice, Catherine; Bearman, Peter – Journal of Autism and Developmental Disorders, 2015
Previous studies report associations between conception with assisted reproductive technology (ART) and autism. Whether these associations reflect an ascertainment or biologic effect is undetermined. We assessed diagnosis age and initial autism symptom severity among >30,000 children with autism from a linkage study of California Department of…
Descriptors: Clinical Diagnosis, Age Differences, Autism, Severity (of Disability)
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Yau, Vincent M.; Lutsky, Marta; Yoshida, Cathleen K.; Lasley, Bill; Kharrazi, Martin; Windham, Gayle; Gee, Nancy; Croen, Lisa A. – Journal of Autism and Developmental Disorders, 2015
Thyroid hormones are critical for normal brain development. This study examined autism spectrum disorders (ASD) and thyroid stimulating hormone (TSH) levels measured in mid-pregnancy maternal serum and infant blood after birth. Three groups of children born in Orange County, CA in 2000-2001 were identified: ASD (n = 78), developmental delay…
Descriptors: Metabolism, Autism, Pervasive Developmental Disorders, Pregnancy
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Rossi, Christy C.; Fuentes, Joaquin; Van de Water, Judy; Amaral, David G. – Journal of Autism and Developmental Disorders, 2014
Previous investigations found that a subset of children with autism spectrum disorder (ASD) in California possessed plasma autoantibodies that reacted intensely with brain interneurons or other neural profiles. Moreover, for several cohorts of American women, maternal autoantibody reactivity to specific fetal brain proteins was highly specific to…
Descriptors: Foreign Countries, Children, Autism, Pervasive Developmental Disorders
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Chaidez, Virginia; Hansen, Robin L.; Hertz-Picciotto, Irva – Journal of Autism and Developmental Disorders, 2014
To compare gastrointestinal (GI) problems among children with: (1) autism spectrum disorder (ASD), (2) developmental delay (DD) and (3) typical development (TD), GI symptom frequencies were obtained for 960 children from the CHildhood Autism Risks from Genetics and Environment (CHARGE) study. We also examined scores on five Aberrant Behavior…
Descriptors: Children, Autism, Pervasive Developmental Disorders, Developmental Delays
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Grether, Judith K.; Qian, Yinge; Croughan, Mary S.; Wu, Yvonne W.; Schembri, Michael; Camarano, Loretta; Croen, Lisa A. – Journal of Autism and Developmental Disorders, 2013
Concerns persist about a possible link between infertility and risk of autism spectrum disorders (ASD). Interpretation of existing studies is limited by racial/ethnic homogeneity of study populations and other factors. Using a case-control design, we evaluated infertility history and treatment documented in medical records of members of Kaiser…
Descriptors: Pregnancy, Autism, Correlation, At Risk Persons
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Froehlich, Wendy; Cleveland, Sue; Torres, Andrea; Phillips, Jennifer; Cohen, Brianne; Torigoe, Tiffany; Miller, Janet; Fedele, Angie; Collins, Jack; Smith, Karen; Lotspeich, Linda; Croen, Lisa A.; Ozonoff, Sally; Lajonchere, Clara; Grether, Judith K.; Hallmayer, Joachim – Journal of Autism and Developmental Disorders, 2013
To determine the genetic relationship between head circumference (HC) and Autism Spectrum Disorders (ASDs). Twin pairs with at least one twin with an ASD were assessed. HCs in affected and unaffected individuals were compared, as were HC correlations in monozygotic and dizygotic pairs. 404 subjects, ages 4-18, were included. 20% of males and 27%…
Descriptors: Twins, Autism, Pervasive Developmental Disorders, Physical Characteristics
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Windham, Gayle C.; Anderson, Meredith C.; Croen, Lisa A.; Smith, Karen S.; Collins, John; Grether, Judith K. – Journal of Autism and Developmental Disorders, 2011
Using standardized methods for multi-source surveillance, we calculated the prevalence of autism spectrum disorders (ASD) among children born in a racially diverse region in 1994 or 1996 as 4.7/1000 live births. Children with ASD before age 9 were identified through chart abstraction at health-related sources; three-quarters were being served by…
Descriptors: Mothers, Incidence, Autism, Pervasive Developmental Disorders
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Grether, Judith K.; Rosen, Nila J.; Smith, Karen S.; Croen, Lisa A. – Journal of Autism and Developmental Disorders, 2009
We investigated if shifts in the coding of qualifying conditions in the California Department of Developmental Services (DDS) have contributed to the increase in California children with autism observed in recent years. Qualifying condition codes for mental retardation (MR) and autism in DDS electronic files were compared to hard-copy records for…
Descriptors: Mental Retardation, Autism, Eligibility, Children
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