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Salomone, Erica; Leadbitter, Kathy; Aldred, Catherine; Barrett, Barbara; Byford, Sarah; Charman, Tony; Howlin, Patricia; Green, Jonathan; Le Couteur, Ann; McConachie, Helen; Parr, Jeremy R.; Pickles, Andrew; Slonims, Vicky; Cole-Fletcher, Rachel; Gammer, Isobel; Maxwell, Jessica; Tobin, Hannah; Vamvakas, George; Cole-Fletcher, Rachle; Gammer, Isobel; Maxwell, Jessica; Tobin, Hannah; Vamvakas, George – Journal of Autism and Developmental Disorders, 2018
We examined predictors of mental health difficulties and wellbeing in caregivers of children with autism in the Pre-school Autism Communication Trial cohort in middle childhood (N = 104). Child's intellectual disability, daily living skills impairment, elevated emotional and behavioural difficulties, high educational level of caregiver and…
Descriptors: Mental Health, Well Being, Autism, Predictor Variables
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Leadbitter, Kathy; Aldred, Catherine; McConachie, Helen; Le Couteur, Ann; Kapadia, Dharmi; Charman, Tony; Macdonald, Wendy; Salomone, Erica; Emsley, Richard; Green, Jonathan; Barrett, Barbara; Barron, Sam; Beggs, Karen; Blazey, Laura; Bourne, Katy; Byford, Sarah; Cole-Fletcher, Rachel; Collino, Julia; Colmer, Ruth; Cutress, Anna; Gammer, Isobel; Harrop, Clare; Houghton, Tori; Howlin, Pat; Hudry, Kristelle; Leach, Sue; Maxwell, Jessica; Parr, Jeremy; Pickles, Andrew; Randles, Sarah; Slonims, Vicky; Taylor, Carol; Temple, Kathryn; Tobin, Hannah; Vamvakas, George; White, Lydia – Journal of Autism and Developmental Disorders, 2018
There is a lack of measures that reflect the intervention priorities of parents of children with autism spectrum disorder (ASD) and that assess the impact of interventions on family experience and quality of life. The Autism Family Experience Questionnaire (AFEQ) was developed through focus groups and online consultation with parents, and…
Descriptors: Pervasive Developmental Disorders, Autism, Questionnaires, Quality of Life
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Salomone, Erica; Shephard, Elizabeth; Milosavljevic, Bosiljka; Johnson, Mark H.; Charman, Tony; Baron-Cohen, Simon; Bedford, Rachael; Bolton, Patrick; Chandler, Susie; Elsabbagh, Mayada; Fernandes, Janice; Garwood, Holly; Gliga, Teodora; Hudry, Kristelle; Jones, Emily J. H.; Pasco, Greg; Pickles, Andrew; Tucker, Leslie; Volein, Agnes – Journal of Autism and Developmental Disorders, 2018
Cognitive and adaptive behaviour abilities early in life provide important clinical prognostic information. We examined stability of such skills in children at high familial risk for ASD who either met diagnostic criteria for ASD at age 7 years (HR-ASD, n = 15) or did not (HR-non-ASD, n = 24) and low-risk control children (LR, n = 37),…
Descriptors: Children, At Risk Persons, Cognitive Ability, Behavior Problems
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Hollocks, Matthew J.; Pickles, Andrew; Howlin, Patricia; Simonoff, Emily – Journal of Autism and Developmental Disorders, 2016
Young people with autism spectrum disorder (ASD) have a high prevalence (~40 %) of anxiety disorders compared to their non-ASD peers. It is unclear whether cognitive and biological processes associated with anxiety in ASD are analogous to anxiety in typically developing (TD) populations. In this study 55 boys with ASD (34 with a co-occurring…
Descriptors: Correlation, Biology, Autism, Pervasive Developmental Disorders
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Grzadzinski, Rebecca; Carr, Themba; Colombi, Costanza; McGuire, Kelly; Dufek, Sarah; Pickles, Andrew; Lord, Catherine – Journal of Autism and Developmental Disorders, 2016
Psychometric properties and initial validity of the Brief Observation of Social Communication Change (BOSCC), a measure of treatment-response for social-communication behaviors, are described. The BOSCC coding scheme is applied to 177 video observations of 56 young children with ASD and minimal language abilities. The BOSCC has high to excellent…
Descriptors: Psychometrics, Validity, Outcomes of Treatment, Measures (Individuals)
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Milosavljevic, Bosiljka; Carter Leno, Virginia; Simonoff, Emily; Baird, Gillian; Pickles, Andrew; Jones, Catherine R.; Erskine, Catherine; Charman, Tony; Happé, Francesca – Journal of Autism and Developmental Disorders, 2016
Alexithymia is a personality trait frequently found in adults with autism spectrum disorder (ASD), and has been linked to impairments in emotion recognition and empathy. The presentation of alexithymia within ASD at younger ages remains unexplored, and was examined in the present study. Alexithymia rates were significantly elevated in ASD (55%;…
Descriptors: Autism, Pervasive Developmental Disorders, Personality Traits, Emotional Response
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de Jonge, Maretha; Parr, Jeremy; Rutter, Michael; Wallace, Simon; Kemner, Chantal; Bailey, Anthony; van Engeland, Herman; Pickles, Andrew – Journal of Autism and Developmental Disorders, 2015
To identify the broader autism phenotype (BAP), the Family History Interview subject and informant versions and an observational tool (Impression of Interviewee), were developed. This study investigated whether the instruments differentiated between parents of children with autism, and parents of children with Down syndrome (DS). The BAP scores of…
Descriptors: Autism, Interviews, Family Environment, Down Syndrome
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Salazar, Fernando; Baird, Gillian; Chandler, Susie; Tseng, Evelin; O'sullivan, Tony; Howlin, Patricia; Pickles, Andrew; Simonoff, Emily – Journal of Autism and Developmental Disorders, 2015
We employed a clinical sample of young children with ASD, with and without intellectual disability, to determine the rate and type of psychiatric disorders and possible association with risk factors. We assessed 101 children (57 males, 44 females) aged 4.5-9.8 years. 90.5% of the sample met the criteria. Most common diagnoses were: generalized…
Descriptors: Preschool Children, Elementary School Students, Comorbidity, Mental Disorders
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Chandler, Susie; Carcani-Rathwell, Iris; Charman, Tony; Pickles, Andrew; Loucas, Tom; Meldrum, David; Simonoff, Emily; Sullivan, Peter; Baird, Gillian – Journal of Autism and Developmental Disorders, 2013
The objective of this study is to investigate whether parentally-reported gastro-intestinal (GI) symptoms are increased in a population-derived sample of children with autism spectrum disorders (ASD) compared to controls. Participants included 132 children with ASD and 81 with special educational needs (SEN) but no ASD, aged 10-14 years plus 82…
Descriptors: Autism, Children, Special Education, Special Needs Students
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Green, Jonathan; Wan, Ming Wai; Guiraud, Jeanne; Holsgrove, Samina; McNally, Janet; Slonims, Vicky; Elsabbagh, Mayada; Charman, Tony; Pickles, Andrew; Johnson, Mark – Journal of Autism and Developmental Disorders, 2013
Theory and evidence suggest the potential value of prodromal intervention for infants at risk of developing autism. We report an initial case series (n = 8) of a parent-mediated, video-aided and interaction-focused intervention with infant siblings of autistic probands, beginning at 8-10 months of age. We outline the theory and evidence base…
Descriptors: Intervention, At Risk Persons, Infants, Autism
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Bishop, Somer L.; Hus, Vanessa; Duncan, Amie; Huerta, Marisela; Gotham, Katherine; Pickles, Andrew; Kreiger, Abba; Buja, Andreas; Lund, Sabata; Lord, Catherine – Journal of Autism and Developmental Disorders, 2013
Research suggests that restricted and repetitive behaviors (RRBs) can be subdivided into Repetitive Sensory Motor (RSM) and Insistence on Sameness (IS) behaviors. However, because the majority of previous studies have used the Autism Diagnostic Interview-Revised (ADI-R), it is not clear whether these subcategories reflect the actual organization…
Descriptors: Autism, Construct Validity, Behavior Disorders, Pervasive Developmental Disorders
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Pickles, Andrew; St Clair, Michelle C.; Conti-Ramsden, Gina – Journal of Autism and Developmental Disorders, 2013
We investigate two aspects of the autism triad, communication and social difficulties, in relatives of specific language impairment (SLI) probands (with and without additional autistic symptomatology) as compared to relatives of autism spectrum disorder (ASD) and Down's syndrome (DS) probands. Findings involving 726 first degree relatives of 85…
Descriptors: Autism, Language Impairments, Family Influence, Siblings
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Bedford, Rachael; Elsabbagh, Mayada; Gliga, Teodora; Pickles, Andrew; Senju, Atsushi; Charman, Tony; Johnson, Mark H. – Journal of Autism and Developmental Disorders, 2012
Whilst joint attention (JA) impairments in autism have been widely studied, little is known about the early development of gaze following, a precursor to establishing JA. We employed eye-tracking to record gaze following longitudinally in infants with and without a family history of autism spectrum disorder (ASD) at 7 and 13 months. No group…
Descriptors: Autism, Infants, At Risk Persons, Social Development
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Barrett, Barbara; Byford, Sarah; Sharac, Jessica; Hudry, Kristelle; Leadbitter, Kathy; Temple, Kathryn; Aldred, Catherine; Slonims, Vicky; Green, Jonathan; Bourne, Katy; Blazey, Laura; Holt, Clare; Kapadia, Dharmi; MacDonald, Wendy; Pickles, Andrew; White, Lydia; Houghton, Tori; Taylor, Carol; Cutress, Anna; Leach, Sue; Le Couteur, Ann; McConachie, Helen; Barron, Sam; Colmer, Ruth; Randles, Sarah; Beggs, Karen; Collino, Julia; Howlin, Pat; Charman, Tony – Journal of Autism and Developmental Disorders, 2012
Autism spectrum disorders (ASD) are associated with a substantial economic burden, but there is little evidence of the costs in the early years; the period in which children are increasingly likely to be diagnosed. We describe the services used by 152 children aged 24-60 months with autism, report family out-of-pocket expenses and productivity…
Descriptors: Community Services, Autism, Family Characteristics, Costs
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Parr, Jeremy R.; Le Couteur, Ann; Baird, Gillian; Rutter, Michael; Pickles, Andrew; Fombonne, Eric; Bailey, Anthony J. – Journal of Autism and Developmental Disorders, 2011
The characteristics of early developmental regression (EDR) were investigated in individuals with ASD from affected relative pairs recruited to the International Molecular Genetic Study of Autism Consortium (IMGSAC). Four hundred and fifty-eight individuals with ASD were recruited from 226 IMGSAC families. Regression before age 36 months occurred…
Descriptors: Autism, Child Development, Pervasive Developmental Disorders, Siblings
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